期刊刊名：南台學報 　 卷期：37卷1期

篇名出版日期：2012年5月1日

作者：Kao-Chang Lin, Huan-Fang Lee, Jinn-Rung Kuo, Jhi-Joung Wang,林高章,李歡芳,郭進榮,王志中

語言：English

關鍵字：Neurotoxin, Memory Tests, Subjective Memory Complaints, Reported Health Consequences, Elderly,神經毒物,記憶功能,主觀記憶抱怨,身體生理狀況,老年人

被點閱次數：6次

閱讀時間：62sec

摘要：
Neurotoxins, such as Polychlorinated biphenyls (PCBs) and polychlorinated dibenzofurans (PCDFs), affect central nervous system functioning. Recent studies have shown that elderly individuals exposed to these toxic compounds have reported memory and learning deficits. Little is known about the reported health status, memory function and memory complaints of these elderly individuals. This study aimed to evaluate memory-related issues and health conditions in elderly individuals exposed to neurotoxin of PCBs and/or PCDFs. We conducted a retrospective cohort study of the Yu-Cheng population in Taiwan. Registered subjects and matched controls (age ≥ 60 years) were recruited. We utilized self-reported health questionnaires and neuropsychological tests of the Wechsler Adult Intelligence Scale-Revised version in Chinese (WAIS-R-III) and the Wechsler Memory Scale-Revised (WMS-R). Memory modalities such as digit symbol (DS), visual memory span (VMS), attention and digit span (ADS), 5-trial verbal memory recalls (VMR), learning ability, 30-min delayed recall, and subjective memory complaints (SMCs) were evaluated. We analyzed a total of 328 subjects; 166 subjects were PCB/PCDF-exposed subjects and 162 were non-exposed subjects. The exposed elderly subjects were more likely to report health conditions such as nail deformity, anemia, asthma, hypertension, and hyperkeratosis. In addition, memory tests revealed a decline in ADS, VMS, learning ability, trial 4 and trial 5 of the VMR, and 30-min delayed recall test results in exposed subjects (p

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