期刊刊名：科技學刊－科技類 　 卷期：16卷1期

篇名出版日期：2007年2月1日

作者：Yuh-Wen Ho, Wei-Hua Yao,何玉文,姚薇華

語言：English

關鍵字：Synthesis, 5-Cyano-1,6-dihydro-4-methyl-2-phenyl-6-thioxopyrimidine, 4-Hydroxy-9-methyl-2-oxo-7-phenyl-2(1H)-pyrido[2,3:4,5]thieno[2,3-d]pyrimidine, Arylazo-pyrido[2,3:4,5]thieno[2,3-d]pyrimidines, 合成,5-氰基-4-甲基-2-苯基-6-硫化嘧啶, 4-氫氧基-9-甲基-2-氧基-7-苯基-吡啶, [2, 3:4, 5]噻哢[2, 3-d]嘧啶, 芳基偶氮吡啶[2, 3: 4, 5]噻哢[2, 3-d]嘧啶衍生物

被點閱次數：2次

閱讀時間：22sec

摘要：
4-Hydroxy-9-methyl-2-oxo-7-phenyl-2(1H)-pyrido[2,3:4,5]thieno[2,3-d]pyrimidine derivative has been synthesized in a simple single step from 5-cyano-1, 6-dihydro- 4-methyl-2-phenyl-6-thioxopyrimidin by cyclocondensation with 4-chlor oacetoacetic acid ethyl ester in DMF in the presence of an excess anhydrous potassium carbonate. The 3-(4-substitutedphehyl)azo-4-hydroxy-9-methyl-2-oxo-7-phenyl-2(1H)-pyrido- [2,3:4,5]thieno[2,3-d]pyrimidine derivatives were also obtained by coupling of 4-hydroxy-9-methyl-2-oxo-7-phenyl-2(1H)-pyrido[2,3:4,5]thieno[2,3-d]pyrimidine with the corresponding diazotized arylamines. The structures of these new compounds were established by examining spectral data (IR, 1H NMR, Mass) and elemental analysis.

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