期刊刊名：健康與照顧科學學刊 　 卷期：1卷2期

篇名出版日期：2012年12月1日

作者：Yi-Fang Lee1, Shu-Lin Lee

語言：English

關鍵字：Sarcopenia, muscle protein synthesis (MPS) , aging, resistance exercise

被點閱次數：6次

閱讀時間：783sec

摘要：
Sarcopenia is an involuntary loss of muscle mass, which may be an intrinsic part of the ageing process rather than the effect of age associated disease. The degradation of muscle mass leads to loss of strength, and eventually to decreased functional status such as poor balance, gait speed, increased risk of falls, fractures, and ultimately an increased risk of mortality. Present guidelines state that physically inactivity or a decreased physical activity level is an important part of the mechanisms of sarcopenia, and therefore physical activity can be seen as an important factor in reversing or modifying the development of sarcopenia. Most research on sarcopenia tends to focus on (1) Preventing muscle protein breakdown and (2) Adequate muscular stimulation in order to increase muscle protein synthesis by resistance training in combination with nutritional intervention (adequate protein and energy intake) . The researches show that exercises and the adequate amounts of dietary protein from high-quality sources are two important ways to increase muscle protein synthesis (MPS) and slow the progression of sarcopenia. Some scholars suggested that intake of 1.5 g protein/kg/day, or about 15-20% of total caloric intake is a target for elderly populations in terms of health and physiology function. Resistance training combined with protein (or amino acid) supplements is utilized frequently to prevent age-related sarcopenia. Therefore, the beneficial interaction between dietary protein or amino acid and resistance exercise has to be considering an effective tool to improve physiology functionality and life quality in older age.

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